Download ATLA Abstracts, Alternatives to Laboratory Animals PDF

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ISBN 10 : UIUC:30112010268453
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Download The History of Alternative Test Methods in Toxicology PDF

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Publisher : Academic Press
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ISBN 10 : 9780128136980
Pages : 352 pages
Rating : 4.1/5 (128 users)

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Download The History of Alternative Test Methods in Toxicology PDF by Full Free and published by Academic Press. This book was released on 2018-10-20 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated, miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing, capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialized areas, such as inhalation toxicity studies. The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement, Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now-classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialised areas, such as inhalation toxicity studies.


Download Abstracts of Alternatives to Laboratory Animals PDF

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ISBN 10 : CORNELL:31924073534236
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Download Current Catalog PDF

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ISBN 10 : UOM:39015074102768
Pages : pages
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Download Current Catalog PDF by National Library of Medicine (U.S.) Full Free and published by . This book was released on 1971 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.


Download Journal Holdings Report PDF

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ISBN 10 : OSU:32435023492234
Pages : pages
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Download Journal Holdings Report PDF by United States. Environmental Protection Agency. Information Management and Services Division Full Free and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Commission on Humane Treatment of Animals PDF

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ISBN 10 : UCR:31210018782514
Pages : 44 pages
Rating : 4.3/5 (312 users)

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Download Commission on Humane Treatment of Animals PDF by United States. Congress. House. Committee on Agriculture. Subcommittee on Livestock and Grains Full Free and published by . This book was released on 1976 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Index of NLM Serial Titles PDF

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ISBN 10 : UOM:39015074114664
Pages : pages
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Download Index of NLM Serial Titles PDF by National Library of Medicine (U.S.) Full Free and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A keyword listing of serial titles currently received by the National Library of Medicine.


Download Hearings, Reports and Prints of the House Committee on Agriculture PDF

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ISBN 10 : UCAL:B3608393
Pages : pages
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Download Hearings, Reports and Prints of the House Committee on Agriculture PDF by United States. Congress. House. Committee on Agriculture Full Free and published by . This book was released on 1976 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Alternatives to Animal Testing PDF

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Publisher : John Wiley & Sons
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ISBN 10 : 9783527616046
Pages : 200 pages
Rating : 4.5/5 (527 users)

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Download Alternatives to Animal Testing PDF by Christoph A. Reinhardt Full Free and published by John Wiley & Sons. This book was released on 2008-11-20 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opinion leaders in science and politics examine findings and legislation in alternatives to animal testing! Refine, reduce, replace - These are the three demands that scientists have placed upon themselves in their search for alternatives to animal testing. Indeed much interdisciplinary research is being carried on today, and new fields have emerged, such as in-vitro toxicology. The three R's call for new scientific insights. Moreover, validation and acceptance strategies have to be adapted, a process of much ongoing interest and vital concern to the pharmaceutical and cosmetic industries. Researchers need to know exactly what has been achieved and accepted in alternatives to animal testing in science and politics. In this book they have the opportunity to benefit from the knowledge and expertise of leading researchers and influential representatives of national and international regulatory authorities.


Download Alternatives to Laboratory Animals PDF

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ISBN 10 : UCLA:L0102975034
Pages : 142 pages
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Download Alternatives to Laboratory Animals PDF by Full Free and published by . This book was released on 2009 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Serials at the National Agricultural Library Relating to Animal Care, Use, and Welfare PDF

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ISBN 10 : MINN:31951D01238489P
Pages : 50 pages
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Download Serials at the National Agricultural Library Relating to Animal Care, Use, and Welfare PDF by Karen J. Clingerman Full Free and published by . This book was released on 1990 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download AWIC Series PDF

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ISBN 10 : WISC:89043816214
Pages : pages
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Download AWIC Series PDF by Full Free and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Index Medicus PDF

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ISBN 10 : UCSD:31822041784174
Pages : pages
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Download Index Medicus PDF by Full Free and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings


Download List of Journals Indexed in Index Medicus PDF

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ISBN 10 : MINN:31951D03111240T
Pages : 308 pages
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Download List of Journals Indexed in Index Medicus PDF by Full Free and published by . This book was released on 2002 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues for 1977-1979 include also Special list journals being indexed in cooperation with other institutions. Citations from these journals appear in other MEDLARS bibliographies and in MEDLINE, but not in Index medicus.


Download List of Journals Indexed for MEDLINE PDF

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ISBN 10 : UOM:39015060289017
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Download List of Journals Indexed for MEDLINE PDF by Full Free and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Alternatives to Animal Experiments PDF

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ISBN 10 : STANFORD:36105003832982
Pages : 228 pages
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Download Alternatives to Animal Experiments PDF by David Henry Smyth Full Free and published by . This book was released on 1978 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Guide to Sources for Agricultural and Biological Research PDF

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Publisher : University of California Press
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ISBN 10 : 9780520328723
Pages : 748 pages
Rating : 4.5/5 (52 users)

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Download Guide to Sources for Agricultural and Biological Research PDF by J. Richard Blanchard Full Free and published by University of California Press. This book was released on 2021-01-08 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1981.