Download Genetically Engineered Mice Handbook PDF

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Publisher : CRC Press
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ISBN 10 : 9781420039078
Pages : 336 pages
Rating : 4.4/5 (42 users)

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Download Genetically Engineered Mice Handbook PDF by John P. Sundberg Full Free and published by CRC Press. This book was released on 2016-04-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: While mice have always been highly popular laboratory subjects, their suitability for genetic engineering has solidified their position as today's lab animal model of choice. However, their increased use in genetic studies has created a demand for input on phenotyping that is not always easily met. To improve the flow of information on the pathology of mice with spontaneous or genetically engineered mutations, prominent researchers organized a series of meetings. Recognizing other needs, the organizers gradually broadened their focus, until finally they expanded to provide an overview of the entire field of genetically engineered models. The Genetically Engineered Mice Handbook is an extension of those meetings. It offers an introduction for those entering into this area of research, while also serving as a resource for those presently employing mice as laboratory models. Highly comprehensive, this volume covers pertinent aspects of genetically engineered mice, including the use of models for developmental biology and the monitoring of laboratory colonies. With contributions from nearly five-dozen leading researchers, the text presents systematic approaches for analyzing mutant mice for specific medical applications, details a variety of methods for creating mutants and includes information that is particularly hard to access dealing with legal responsibilities. This essential reference examines commonly used traditional, as well as emerging, technologies To address the purpose of the original meeting, the Genetically Engineered Mice Handbook directs researchers to the best public websites, and offers instruction on how to use them. In the past, as their work dictated, researchers would seek out experts on particular organ systems. Now groups of experts work together to generate these websites, providing the latest data as well as discussions over points of debate. These sites do not eliminate the need for a trained pathologist, but they do provide reference materials for those lacking expertise in particular anatomic structures. They also offer much greater numbers of examples than are available in print, from which biomedical researchers can draw.


Download Raising Cats Naturally PDF

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Publisher : Lulu.com
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ISBN 10 : 9781427605344
Pages : 161 pages
Rating : 4.4/5 (427 users)

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Download Raising Cats Naturally PDF by Michelle T. Bernard Full Free and published by Lulu.com. This book was released on 2004-02-01 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's about time we had a book like this. Michelle Bernard has a rare gift for putting in plain words extraordinarily effective and levelheaded ways to properly care for cats. Steering clear of faddish, dangerous trends-and dissecting the oodles of misinformation that has regrettably become the norm in mainstream advice on animal nutrition-she shines most conspicuously on the issue of a proper feline diet. By giving the reader a common-sense, straightforward strategy for preparing a diet that is based solely on the nutritional requirements of true carnivores, her book is a must-have for anyone committed to building and maintaining glowing good health for cats. Bernard's work on all aspects of caring naturally for cats is based on years of meticulous research and hands-on experience, yet she translates her knowledge into simple, common sense guidelines that anyone can understand and put to use. Her eloquent explanation of homeopathy demystifies this splendid, ancient healing art that is so marvelously suited to cats, giving the reader a valuable awareness about how to build and nurture a cat's health from the inside out. This alone is a refreshing and most welcome approach given the routine over-medication and over-vaccination of cats. If you love your cat, read this book. All of it.



Download Advances In Animal Alternatives For Safety And Efficacy Testing PDF

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Publisher : CRC Press
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ISBN 10 : 1439805814
Pages : 474 pages
Rating : 4.8/5 (85 users)

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Download Advances In Animal Alternatives For Safety And Efficacy Testing PDF by Harry Salem Full Free and published by CRC Press. This book was released on 1997-11-12 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents up-to-date concepts and approaches to the theory and practice of alternatives to animal testing and promotes technology transfer. The text addresses some of the ramifications of the National Institutes of Health Revitalization Act of 1993 which instructs the NIH to fund replacement, reduction and refinement alternatives. It also describes


Download Systematic Evaluation of the Mouse Eye PDF

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Publisher : CRC Press
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ISBN 10 : 9781420041606
Pages : 383 pages
Rating : 4.4/5 (42 users)

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Download Systematic Evaluation of the Mouse Eye PDF by Richard S. Smith Full Free and published by CRC Press. This book was released on 2001-12-20 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completion of the first phase of the Human Genome Project has presented scientists with a mountain of new information. The availability of all human genes and their locations is exciting, but their mechanisms of action and interaction with other genes are often unknown. Certain variations in the environment and characteristics of human genes make i


Download Adult Stem Cell Therapies: Alternatives to Plasticity PDF

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Publisher : Springer
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ISBN 10 : 9781493910014
Pages : 266 pages
Rating : 4.4/5 (493 users)

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Download Adult Stem Cell Therapies: Alternatives to Plasticity PDF by Mariusz Z. Ratajczak Full Free and published by Springer. This book was released on 2014-09-10 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely volume explores various techniques for tissue and organ regeneration using stem cells isolated from adult tissues. It discusses alternative explanations of stem cell plasticity as well as current clinical results with adult stem cell therapies. It examines the presence of potential pluripotent stem cells in adult tissues, paracrine effects of stem cell therapies, and involvement of exosomes and microparticles into observed phenomena. Fifteen chapters, all written by noted leaders of their fields, focus on a variety of topics including cord blood and hematopoietic stem cells, skin and tissue organ regeneration, very small embryonic-like stem cells, and cell therapies in cardiology, neonatology, and neurology. Edited by Dr. Mariusz Ratajczak, an internationally known specialist in adult stem cell biology, Adult Stem Cell Therapies: Alternatives to Plasticity is an important addition to the Stem Cell Biology and Regenerative Medicine series.


Download History of Meat Alternatives (965 CE to 2014) PDF

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Publisher : Soyinfo Center
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ISBN 10 : 9781928914716
Pages : 1437 pages
Rating : 4.9/5 (928 users)

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Download History of Meat Alternatives (965 CE to 2014) PDF by William Shurtleff Full Free and published by Soyinfo Center. This book was released on 2014-12-18 with total page 1437 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world's most comprehensive, well documented and well illustrated book on this subject. With extensive index. 435 color photographs and illustrations. Free of charge in digital PDF format on Google Books.


Download Textbook of Assisted Reproductive Techniques PDF

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Publisher : CRC Press
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ISBN 10 : 9781498740104
Pages : 1040 pages
Rating : 4.4/5 (498 users)

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Download Textbook of Assisted Reproductive Techniques PDF by David K. Gardner Full Free and published by CRC Press. This book was released on 2017-11-09 with total page 1040 pages. Available in PDF, EPUB and Kindle. Book excerpt: Already established as a classic comprehensive reference for the whole team at the IVF clinic, this new edition has been extensively revised, with the addition of several important new contributions on laboratory ( including advanced sperm selection techniques for ICSI, human embryo biopsy procedures, oocyte activation, managing an oocyte bank, artificial gametes, and epigenetics) as well as on clinical topics (including GnRH agonist triggering, segmentation of IVF treatment, uterus transplantation, and risk and safety management). As previously, methods, protocols, and techniques of choice are presented by eminent contributors internationally.


Download Textbook of Assisted Reproductive Techniques Fourth Edition PDF

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Publisher : CRC Press
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ISBN 10 : 9781841849720
Pages : 508 pages
Rating : 4.8/5 (841 users)

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Download Textbook of Assisted Reproductive Techniques Fourth Edition PDF by David K. Gardner Full Free and published by CRC Press. This book was released on 2012-06-27 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Assisted Reproductive Technologies has become a classic comprehensive reference for the whole team at the IVF clinic. The fourth edition comes more conveniently as a set of two separate volumes, one for laboratory aspects and the other for clinical applications. The text has been extensively revised, with the addition of several important new contributions on clinical applications, including new chapters on lifestyle factors, tailored ovarian stimulation, frozen-thawed embryo transfer, viral disease, and religious perspectives. As before, methods, protocols, and techniques of choice are presented by eminent international experts. Also available - Textbook of Assisted Reproductive Technologies, Volume One - Laboratory Perspectives Textbook of Assisted Reproductive Technologies, Two Volume Set


Download Alternatives to Laboratory Animals PDF

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ISBN 10 : UCLA:L0099053266
Pages : 522 pages
Rating : 4.:/5 ( users)

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Download Alternatives to Laboratory Animals PDF by Full Free and published by . This book was released on 2008 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Transgenesis Techniques PDF

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Publisher : Springer Science & Business Media
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ISBN 10 : 9781592591787
Pages : 346 pages
Rating : 4.5/5 (592 users)

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Download Transgenesis Techniques PDF by Alan R. Clarke Full Free and published by Springer Science & Business Media. This book was released on 2002 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has witnessed a spectacular explosion in both the development and the use of transgenic technologies. In Transgenesis Techniques: Principles and Protocols, Second Edition, authoritative researchers-including members of the Dolly team-take stock of these exciting developments to present a collection of readily reproducible techniques for the generation and analysis of transgenic animals, focusing on the manipulation of the mammalian genome. This second edition devotes much space to the creation of genetically modified murine strains, providing access to the germline both by conventional pronuclear injection and by retroviral and adenoviral infection. Extensive coverage is also given to the generation, maintenance, and manipulation of embryonic stem cell lineages, with protocols for both constitutive and conditional (Cre-lox or the Flp-frt systems) gene targeting. Additional chapters provide cutting-edge techniques for the cryopreservation of both male and female germlines, for the generation of transgenic sheep by nuclear transfer, and for the basic analysis of transgenic organisms. Comprehensive and highly practical, this second edition of Transgenesis Techniques: Principles and Protocols updates and expands the acclaimed first edition with a wealth of easy-to-follow cutting-edge protocols and practical tips for producing transgenic animals and analyzing their integrated transgenes.


Download Index Medicus PDF

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ISBN 10 : OSU:32436011091418
Pages : 2232 pages
Rating : 4.3/5 (324 users)

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Download Index Medicus PDF by Full Free and published by . This book was released on 2003 with total page 2232 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU PDF

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Publisher : Academic Press
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ISBN 10 : 9780128212523
Pages : 346 pages
Rating : 4.1/5 (128 users)

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Download Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU PDF by Gianni Dal Negro Full Free and published by Academic Press. This book was released on 2021-11-18 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU provides updated information on the EU Directive 2010/63/EU, which is the European Union legislation that protects animals being used in research. EU Directive 2010/63/EU is the European Union (EU) legislation 'on the protection of animals used for scientific purposes' and is one of the most stringent ethical and welfare standards worldwide. Closes a gap in scientific literature by addressing the need for clear guidance in walking through the multifaced universe of 3Rs Offers a useful starting point for readers and scientist who approach the 3Rs for the first-time Gives insights into the harmonization of the animal research legislation across countries


Download Monoclonal Antibodies and Functional Cell Lines PDF

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Publisher : Springer Science & Business Media
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ISBN 10 : 9781468446739
Pages : 426 pages
Rating : 4.4/5 (468 users)

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Download Monoclonal Antibodies and Functional Cell Lines PDF by Roger H. Kennett Full Free and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume serves as a follow-up to our previous book, MonoclonalAntibodies Hybridomas: A New Dimension in Biological Analyses. We continue the theme of monoclonal antibodies and their applications, attempting to cover some of the areas not covered in the previous volume. We again include an appendix de scribing methods useful to those who ar-e beginning to apply these techniques in their own laboratories. This volume will be followed by another concentrating on the combination of monoclonal antibody techniques with molecular genetic techniques to study structure/function relationships at the level of both the gene and gene product. Roger H. Kennett Kathleen B. Bechtol Philadelphia, Pennsylvania Thomas J. McKearn Princeton, New Jersey IX Acknowledgments Roger Kennett acknowledges the patience and support of his wife, Carol, and his family, friends, and colleagues during the work on this volume, and again thanks, above all, the Lord, Jesus Christ. Kathleen Bechtol wishes to thank colleagues and friends for their support and understanding during the months of preparation of this volume. Tom McKearn acknowledges and thanks his wife, Pat, and his family for their support and encouragement. Xl Contents PART I INTRODUCTION 1 Introduction: Reflections on Nine Years of Monoclonal Antibodies from Hybridomas 3 ROGER H. KENNETT, KATHLEEN B. BECHTOL, AND THOMAS J. McKEARN 1. Biotechnology'S "Coming of Age". . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 II. Monoclonal Antibodies-An Overview of Applications. . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 III. Commercialization of Monoclonal Antibody Technology.. . . .. ... . .... .... .. . ... . . 10 References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 . . . . . . . . . . . . . . . . . . . . .


Download ATLA Abstracts, Alternatives to Laboratory Animals PDF

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ISBN 10 : UIUC:30112010268453
Pages : pages
Rating : 4.:/5 (3 users)

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Download ATLA Abstracts, Alternatives to Laboratory Animals PDF by Full Free and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Alternative Testing Methodologies PDF

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ISBN 10 : IND:30000143535981
Pages : 404 pages
Rating : 4.3/5 (3 users)

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Download Alternative Testing Methodologies PDF by Full Free and published by . This book was released on 1998 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Issues in Animal Science and Research: 2011 Edition PDF

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Publisher : ScholarlyEditions
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ISBN 10 : 9781464965081
Pages : 1113 pages
Rating : 4.4/5 (464 users)

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Download Issues in Animal Science and Research: 2011 Edition PDF by Full Free and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 1113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Animal Science and Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Animal Science and Research. The editors have built Issues in Animal Science and Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Animal Science and Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Animal Science and Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.